SOCS2 inhibitors
kent448 MTN III
Breastmilk...
5.4 P/M
1.25 C/L
mirin 4 | 0 |
May 8 2026 |
LOOKSMAXXING

LAMOTRIGINE AND CINNARIZINE


SOCS2 protein responsible for the sensitivity of cells to growth hormone (GH).


Deficiency leads to gigantism, excess to dwarfism.


Mice with SOCS2 deficiency are 30-50% larger, 1.3-1.5 times


SOCS-2(-/-) mice significantly exceeded their wild relatives in size. The increase in body weight became evident after weaning and was associated with a significant increase in the length of long bones and a proportional increase in most organs


Quoting from a study where they were looking for drugs (to suppress SOCS2 and CEBPD) for treatment:


"Non-alcoholic fatty liver disease (NAFLD)


In addition, lamotrigine, cinnarizine, and lenvatinib significantly suppressed the expression of CEBPD and SOCS2 induced by FFA in HepG2 cells (p  < 0.05), confirming their potential regulatory effect.


In my opinion cinnarizine seems the best option here.

no comments, shitpost basically.